USMLE Step 1 Self Paced Course

Cells of immune system

Lymphoid structures

Lymphatic drainage

Secondary Lymphoid structures- The Spleen and Lymph nodes

Innate vs adaptive immunity

MHC class I and II

HLA and disease associations

T cell activation and immunity

B cells-antibodies and humoral immunity

interleukins overview

Active vs passive immunity

vaccinations

Hypersensitivity response

Blood transfusion reactions

T cell disorders

B cells immunodeficiency disorders

B and T cell disorders

Transplant rejection and Grafts

Introduction to vitamins

Introduction to metabolism

Vitamins

Lysosomal storage diseases

Respiratory Burst

Sorbitol

Pyruvate metabolism

Glycolysis

Glycogen synthesis- storage diseases

Fructose metabolism

Citric acid (Kreb) cycle

Electron transport chain

Pyruvate kinase deficiency

Phenylketonuria

Maple syrup urine disease

Urea Cycle

Lactase deficiency

Ketones

Homocysturia

Fatty Acid Synthesis and beta oxidation

Ethanol metabolism

Catecholamine synthesis

Amino acid metabolism

Alkaptonuria

Albinism

Malnutrition

EPIDEMIOLOGY and BIOSTATISTICS.

Types of studies

Clinical Trial

Sensitivity and Specificity

Incidence vs Prevalence.

Quantifying Risk Quantification

Precision vs Accuracy

Bias and Study Errors

Statistical distribution

Statistical hypotheses

Outcomes of Statistical hypothesis testing

Meta Analysis

Confidence interval

Chi square, T-test and analysis of variance

Pearson correlation coefficient (r)

Disease prevention

Medicare and Medicaid

ETHICS

Core ethical principles

Informed consent

Consent for minors

Decision-making capacity

Advance directives

Surrogate decision- maker

Confidentiality

Ethical situations

DEVELOPMENT

Cell injury and changes

Cell Adaptation

Apoptosis

Necrosis

Acute inflammation

Chronic inflammation

Granulomatous inflammation

Wound healing and repair

Bacteria Cell Wall Function

Bactrial Classification Algorithm

Bacteria Morphology

Bacteria Staining Techniques

Microbiology Exotoxins

Bacteria Growth Curve

Bacteria Endotoxin

Aerobes And Anerobes

Gram Positive Bacteria

Yersinia Enterocolitica

Vibrio

Tuberculosis

Spirochetes

Viral Structure And Genetics

RNA Viruses

DNA Viruses

Rickettsia

Pseudomonas Aeroginosa

Neisseria

Mycoplasma Pneumoniae

Mycology

Legionella Pneumophila

Klebsiella

Hiv

Helicobacter Pylori

Haemophilus Influenzae

Gardenerella Vaginalis

Opportunistic Fungal Infections

E.Coli

Chlamydia

Campylobacter Jejuni

Bordetella Pertussis

Microbiology High Yield Review

Acute Appendicitis
Acute Gastritis
Acute Pancreatitis
Acute Mesenteric Ischemia
Carcinoid syndrome
Cholecystitis
Choledocolithasis/ Ascending Cholangitis
Cholelithiasis- Gallstone Pathology
Chronic Pancreatitis
Diseases of the Esophagus: Achalasia
Diseases of the Esophagus: Diffuse Esophageal Spasm
Diseases of the Esophagus: Esophageal Cancer
Diseases of the Esophagus: Esophagitis
Diseases of the Esophagus: Introduction
Esophageal Diverticula/Zenkers Diverticulum
Diverticulosis/Diverticulitis
Gastroesophageal Reflux Disease (GERD)
Gastrointestinal Bleeding
Hemochromatosis
Hepatitis B
Hepatocellular Carcinoma
Inflammatory Bowel Disease: Crohns Disease
Inflammatory Bowel Disease II: Ulcerative colitis
Jaundice – Hyperbilirubinemia
Liver Cirrhosis
Liver Function Test (AST/ALT)
Peptic Ulcer Disease (PUD)
Primary Biliary Cirrhosis
Primary sclerosing Cholangitis
Small Bowel Obstruction
pancreatic adenocarcinoma
Wilson’s Disease
Hereditary hyperbilirubinemia
Reye’s syndrome
Colon cancer
Intestinal disorders
Duodenal atresia
Hirschsprungs disease
intussucception and volvulus
Meckels Diverticulum
Celiac sprue
Pyloric stenosis
Liver anatomy

Male reproductive anatomy

Spermatogenesis and androgens

Female reproductive cycle

Preeclampsia

Pregnancy complications

Placenta Previa

Placenta Accreta

Placenta Abruption

Polycystic ovarian syndrome

Sex Chromosomes Disorders

Klinefelters syndrome

Turner’s syndrome
Androgen insensitivity syndrome

5 alpha reductase deficiency

Kallman syndrome

Hydatidiform mole

Ectopic pregnancy

Endometriosis

Endometrial pathology

Myometrial tumors

cervical cancer

Ovarian Tumors

Breast Tumors

Benign Prostatic Hyperplasia

Prostate cancer

Testicular disorders

Urinary Tract Infection

Autosomal dominant Polycystic Kidney Disease

Horseshoe Kidney

Angiomyolipoma

Renal Cell Carcinoma

Renal Tubular Acidosis (RTA)

Transitional Cell Carcinoma

Wilms tumor

Rhabdomyolysis

Respiratory Alkalosis

Renin-Angiotensin-Aldosterone system (Blood pressure Regulation)

Nsaids Nephropathy/ Renal Papillary Necrosis

Nephrotic syndrome

Nephritic Syndrome

Chronic Renal Failure Part 2: Uremia Induced bleeding

Chronic Renal Failure Part 1

Acute Tubular Necrosis

Acute Renal Failure

Acute Interstitial Nephritis

Acid-base Disorders: Introduction to the Basics

Acid-Base Disorder: Respiratory Acidosis

Acid-base disorder: Metabolic Alkalosis

Acid-base Disorder: Metabolic Acidosis

Coronary circulation lecture
Heart sounds basics
Congestive heart failure
Deep venous thrombosis (DVT)
Disease of Vasculature: Hypertensive Emergency
Diseases of Vasculature: Abdominal Aortic Aneurysm
Diseases of Vasculature: Abdominal Aortic dissection
EKG lectures tutorial
Introduction to EKG physiology
EKG: Atrial Fibrillation
EKG: Heart Blocks
EKG Tutorials: How to read a Normal EKG
EKG Tutorials: Supraventricular Tachycardia
Introduction to Hypertension
Hypertension Part 2
Infective Endocarditis
Ischemic Heart Disease: Acute Coronary Syndrome
Wolff parkinson white syndrome animation
Complication of Acute Myocardial Infarction
Ischemic Heart Disease: Prinzmetals Angina
Ischemic Heart Disease: Stable Angina
Pericardial Diseases: Acute Pericarditis
Pericardial Diseases: Cardiac Tamponade
Peripheral Vascular Disease: Atherosclerosis
SHOCK: Understanding the Basics of Shock
SHOCK: Cardiogenic Shock
SHOCK: Hypovolemic Shock
SHOCK: Neurogenic Shock
SHOCK: Septic Shock
Valvular Heart Disease: Aortic Stenosis
Valvular Heart Disease: Mitral Regurgitation
Valvular Heart Disease: Mitral Stenosis
Valvular Heart Disease: Tricuspid Regurgitation
Blood pressure Regulation II:: Renin-Angiotensin-Aldosterone system
Blood Pressure Regulation I: Baroreceptor Pathway
Cardiology Arrythmias Animations
Congenital Heart Disease: Atrial Septal Defect (ASD)
Congenital Heart Disease: Ventricular Septal Defect (VSD)

1. Demyelination Disorders I: Multiple Sclerosis

2. Demyelination Disorders II: Gullian Barre Syndrome

3. Duchenne’s Muscular Dystrophy

4. Epidural & Subdural Hematomas

5. Head Trauma: Intracranial Pressure (ICP)

6. Hemorrhagic Stroke: Intracranial & Subarachnoid Hemorrhage

7. Movement Disorders 1: Basal Ganglia Structure & Function

8. Movement Disorders 2: Parkinsons Disease

9. Movement Disorders 3: Huntington’s Disease

10. Myasthenia Gravis

11. Seizures

12. Stroke Part 1: Circle of Willis Anatomy

13. Stroke Part 2: Cerebrovascular Diseases

14. Stroke Part 3: Cerebrovascular Diseases (Diagnosis & Treatment)

15. Cranial Nerves and clinical application

16. Ventricular system pathology

17. Spinal cord pathways

18. Spinal cord lesions

19. Brain tumors

20. Headaches

21. Glaucoma

22. Dementia and Delirium

23. Neurocutaneous syndromes

Brachial Plexus

Crystal Induced Arthritides: Gout

Crystal Induced Arthritides: Pseudogout

Inflammatory Bowel Disease: Crohns Disease

Inflammatory Bowel Disease: Ulcerative Colitis

Origins and insertions of upper extremities

Origins and insertions III

Polymyalgia Rheumatica

Polymyositis & Dermatomyositis

Rheumatoid Arthritis (RA)

scleroderma (System Sclerosis)

Seronegative Arthropathy: Ankylosing spondylitis

Seronegative Arthropathy: Psoaritic Arthritis

Seronegative Arthropathy: Reactive Arthritis

Sjogren’s Syndrome

Systemic Lupus Erythematosus

Vasculitis

1. Anemia Part 1: The Red Blood Cell

2. Anemia Part 2: Heme Synthesis

3. Anemia Part 3: Basics to Anemia

4.Anemia Part 4: Microcytic Anemia- Iron Deficiency Anemia

5. Anemia Part 4a: Microcytic Anemia- Sideroblastic Anemia

6.Anemia Part 4b: Microcytic Anemia- Thalassemia

7. Anemia Part 4d: Microcytic Anemia- Anemia of Chronic DIsease

8. Anemia Part 4e: Normocytic anemia- Aplastic Anemia

9. Anemia Part 5: Macrocytic Anemia- Vitamin B12 Deficiency Anemia

10. Anemia Part 5b: Macrocytic Anemia-Folate Deficiency

11. Anemia Part 6: Hemolytic Anemia- Hemolytic Anemia & Hereditary Spherocytosis

12. Anemia Part 7: Hemolytic Anemia- Paroxysmal Nocturnal Hemoglobinuria (PNH)

13. Anemia Part 8: Hemolytic Anemia- G6PD deficiency

14. Anemia Part 9: Hemolytic Anemia- Autoimmune Hemolytic Anemia

15. Anemia Part 9b: Hemolytic Anemia- Sickle Cell disease

16. Coagulation Disorder: Disseminated Intravascular Coagulopathy (DIC)

17. Coagulation Disorder: Hemophilia A & B

18. Coagulation Disorder: Von Willebrands Disease

19. Lymphoma: Hogdkins Disease

20. Lymphoma II: Non-Hogdkins Lymphoma

21. Leukemia II: Chronic Myelogenous Leukemia (CML) & Chronic Lymphocytic leukemia (ALL)

22. Leukemia: Acute Myelogenous Leukemia (AML) & Acute Lymphocytic leukemia (ALL)

23. plasma cell dyscrasia: Multiple Myeloma

24. Platelet Disorder Part 1: Bleeding disorders (platelet Vs Clotting factors disorders)

25. Platelet Disorder Part 2: Thrombocytopenia (Introduction)

26. Platelet Disorder Part 3: Immune Thrombocytopenic Purpura (ITP)

27. Platelet Disorder: Thrombotic Thrombocytopenia Purpura (TTP)

28. The Clotting/Coagulation Cascade

29. Waldenstrom Macroglobulinemia

Adrenal Gland Physiology
Adrenal Insufficiency
Diabetes Insipidus
Diabetes Mellitus (DM)
Diabetic ketoacidosis (DKA)
Diseases of pituitary gland: Acromegaly
Diseases of the Adrenal Gland: Pheochromocytoma
Diseases of the Adrenal Glands: Cushings Syndrome
Diseases of the Parathyroid Glands: Hyperparathyroidism
Diseases of the parathyroid glands: Hypoparathyroidism
Diseases of the thyroid gland: Hyperthyroidism
Diseases of the thyroid gland: Hypothyroidism
Diseases of the thyroid gland: Thyroid Storm
Diseases of the thyroid gland: Thyroiditis
Hyperosmolar Non-ketosis Syndrome (HHNS)
Hypoglycemia
Insulinoma
Multiple Endocrine Neoplasia (MEN Syndrome)
Parathyroid Physiology (Calcium Regulation)
Pituitary Gland Physiology: Prolactinoma
Primary Hyperaldosteronism
Syndrome of Inappropriate ADH (SiADH)
Thyroid Gland Pharmacology
Thyroid Gland Physiology
VIPOMA
Zollinger Ellison Syndrome/ Gastrinoma
Diabetes: Complications

Acute Respiratory Failure (ARF)
Adult Respiratory Distress Syndrome (ARDS)
Asthma
Chronic Obstructive Pulmonary Disease (COPD)
Cystic Fibrosis
Diseases of Pulmonary Vasculature: Cor Pulmonale
Diseases of Pulmonary Vasculature: Primary Pulmonary Hypertension
Diseases of Pulmonary Vasculature: Pulmonary Hypertension
Goodpastures Syndrome
Interstitial Lung Disease (ILD)- Introduction
Interstitial Lung Diseases: Idiopathic Pulmonary Fibrosis
Interstitial Lung Diseases: Sarcoidosis
Lung Cancer
Pleural Effusions
Pneumoconiosis
Pneumoconiosis: Asbestosis
Pneumoconiosis: Berryliosis
Pneumoconiosis: Coal Worker Disease (CWP)
Pneumoconiosis: Silicosis
Pneumonia
Pulmonary Embolism (PE)
Respiratory Physiology: Flow-Volume loops
Tuberculosis